Covalent vs Non-Covalent Interactions in Biomolecules
The structure and function of biological macromolecules are governed by a delicate balance between covalent vs non-covalent interactions. Covalent bonds provide the fundamental chemical framework of biomolecules, ensuring stability and continuity of structure, whereas non-covalent interactions—though individually weaker—collectively determine the three-dimensional conformation, dynamics, and specificity of molecular recognition. In life …